1 00:00:00,000 --> 00:00:04,250 Thymosin alpha-1 is studied for effects on immune function. 2 00:00:04,250 --> 00:00:10,917 Whether an immune signal changes is a different question from whether patients survive serious illness. 3 00:00:10,917 --> 00:00:17,167 The TESTS trial enrolled more than eleven hundred adults with sepsis across Chinese centres. 4 00:00:17,167 --> 00:00:21,417 Participants received thymosin alpha-1 or placebo alongside standard care. 5 00:00:21,417 --> 00:00:26,875 The analysis did not demonstrate a reduction in deaths within twenty-eight days. 6 00:00:26,875 --> 00:00:33,125 A published correction updated some calculations without turning this into a positive mortality finding. 7 00:00:33,125 --> 00:00:37,000 That result applies to this trial and setting. 8 00:00:37,000 --> 00:00:43,250 It neither proves all possible uses ineffective nor establishes a general immune-boosting benefit in 9 00:00:43,250 --> 00:00:46,750 healthy people.