NAD+: Follow the Measurement
AXON Research Institute • AXON Peptide affiliation
Educational draft • Scientific + legal review pending
Silent film with full on-screen captions. Conceptual illustrations, not molecular structures.

NAD+ is a coenzyme involved in cellular energy reactions. Its essential biological role does not, by itself, establish benefits from adding more. A 2019 pilot study assigned eleven men to NAD+ or saline and tracked blood and urine chemistry around a six-hour research infusion. Researchers observed changes in NAD+ and related metabolites. That answers questions about what happens to the compound, rather than whether people live longer. The study was small and brief. It cannot establish lasting improvements in energy, cognition or aging, or reliably detect uncommon and delayed harms.

END CARD
Educational draft. Not medical advice. Sources and limitations accompany this film.

SOURCES
[1] Grant et al. (2019): A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+
https://pmc.ncbi.nlm.nih.gov/articles/PMC6751327/
Primary small randomized human metabolic pilot

EVIDENCE LIMITATIONS
Eleven healthy male participants and an eight-hour sampling window limit generalizability.
This is a metabolism study, not evidence for longevity, cognition or generalized wellness claims.
Short-term tolerability in a small pilot cannot exclude uncommon or delayed risks.

TOPIC INVENTORY PROVENANCE (not reused audiovisual media)
NAD+: A Coenzyme, a Biomarker and an Intervention Are Different Questions