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Klotho is a protein studied in aging biology.

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Its name appears in both biomarker research and experiments that administer a defined protein

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preparation.

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A 2023 study tested klotho in mice and aged rhesus monkeys.

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The primate experiments measured performance on a task requiring memory of a reward location.

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Researchers reported improved memory performance under particular experimental conditions.

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That finding concerns an animal task, not proof of preventing dementia or restoring human cognition.

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Different protein forms and experimental conditions need to remain identifiable.

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The study supports further research, while human effectiveness, durability, and safety require their own

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clinical evidence.