1 00:00:00,000 --> 00:00:03,500 VK2735 activates GIP and GLP-1 receptors. 2 00:00:03,500 --> 00:00:09,750 Its research includes different formulations, making the route of administration an important part of 3 00:00:09,750 --> 00:00:13,250 every evidence claim. 4 00:00:13,250 --> 00:00:20,333 The phase two VENTURE study tested the injectable formulation against placebo in adults with obesity or 5 00:00:20,333 --> 00:00:23,833 overweight and a related condition, excluding diabetes. 6 00:00:23,833 --> 00:00:28,917 Over 13 weeks, the study reported greater body-weight reduction with VK2735. 7 00:00:28,917 --> 00:00:32,417 The most common adverse events were gastrointestinal. 8 00:00:32,417 --> 00:00:35,917 These are short-term trial findings. 9 00:00:35,917 --> 00:00:41,375 An oral formulation needs its own evidence on absorption, tolerability, and outcomes. 10 00:00:41,375 --> 00:00:48,042 Results from an injectable study cannot establish equivalent performance for a tablet or an unrelated 11 00:00:48,042 --> 00:00:51,542 research product.