1
00:00:00,000 --> 00:00:05,875
AOD-9604 has been studied for two very different questions: body weight and cartilage.

2
00:00:05,875 --> 00:00:10,125
Following the evidence means keeping those research programs separate.

3
00:00:10,125 --> 00:00:14,375
It was developed from part of the growth-hormone sequence.

4
00:00:14,375 --> 00:00:21,042
An obesity trial did not show a significant weight-loss advantage over placebo, and that development

5
00:00:21,042 --> 00:00:24,542
program was stopped.

6
00:00:24,542 --> 00:00:29,625
Later cartilage research included an experimentally induced knee-arthritis model in rabbits.

7
00:00:29,625 --> 00:00:35,083
Tissue findings in that model cannot establish that AOD-9604 repairs human joints.

8
00:00:35,083 --> 00:00:40,167
A new research angle does not erase an earlier trial result.

9
00:00:40,167 --> 00:00:46,833
Each proposed use needs convincing human benefit, safety data, and evaluation of the actual formulation.