Oxytocin: What a Dog’s Gaze Can Tell Us AXON Research Institute • AXON Peptide affiliation Educational draft • Scientific + legal review pending Silent film with full on-screen captions. Conceptual illustrations, not molecular structures. A familiar dog looks up at you. Could that everyday moment involve a hormone? Researchers have studied oxytocin as one part of human–dog bonding. A 2015 study linked dogs’ gazing behavior with changes in their owners’ urinary oxytocin. An additional experiment tested oxytocin in dogs, not a bonding treatment in people. Urine measurements and a particular interaction cannot capture the whole biology of trust. Effects also depend on context, and one hormone does not explain a relationship. Medical oxytocin has specific obstetric uses, including selected labor care and postpartum bleeding. Those indications do not establish a treatment for loneliness or stronger bonds. END CARD Research explained. Not medical advice. Sources and limitations in the accompanying transcript. SOURCES [1] Nagasawa et al. (2015): Oxytocin-gaze positive loop and human–dog bonds https://pubmed.ncbi.nlm.nih.gov/25883356/ Primary human–animal study [2] DailyMed: Oxytocin injection label https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7fd585a-99b7-4309-b003-a6cbef05372c US prescribing information EVIDENCE LIMITATIONS Urinary oxytocin is an indirect measurement and is not a complete measure of central signaling. Do not infer that administering oxytocin to a person improves a relationship. The original study is not a clinical efficacy or long-term safety trial for a social indication. TOPIC INVENTORY PROVENANCE (not reused audiovisual media) https://www.facebook.com/reel/1482685473672504/