1 00:00:00,000 --> 00:00:04,250 CJC-1295 and ipamorelin approach growth-hormone signalling through different routes. 2 00:00:04,250 --> 00:00:09,708 That is a mechanism story, not yet proof of a useful combination. 3 00:00:09,708 --> 00:00:13,208 CJC-1295 is a growth-hormone-releasing-hormone analogue. 4 00:00:13,208 --> 00:00:16,708 Ipamorelin is a growth-hormone secretagogue. 5 00:00:16,708 --> 00:00:20,958 Their individual pharmacology explains why people discuss them together. 6 00:00:20,958 --> 00:00:26,833 Small human studies of long-acting CJC-1295 measured increases in growth hormone and IGF-one. 7 00:00:26,833 --> 00:00:32,292 They did not establish that adding ipamorelin improves health, strength or longevity. 8 00:00:32,292 --> 00:00:36,167 FDA has raised safety concerns about these substances. 9 00:00:36,167 --> 00:00:43,250 Also check the exact CJC formulation: products described as with or without DAC cannot inherit one 10 00:00:43,250 --> 00:00:46,750 another’s evidence.