1 00:00:00,000 --> 00:00:04,667 How does a three-amino-acid peptide get inside a gut cell? 2 00:00:04,667 --> 00:00:08,917 That question sits at the centre of KPV research. 3 00:00:08,917 --> 00:00:15,167 In laboratory-grown intestinal and immune cells, researchers found that a transporter called PepT1 could 4 00:00:15,167 --> 00:00:18,667 carry KPV inside. Inflammatory signalling then changed. 5 00:00:18,667 --> 00:00:23,750 The same research reported reduced inflammation in mouse models of colitis. 6 00:00:23,750 --> 00:00:30,000 Human-derived cells and mice are useful steps, but neither establishes treatment benefits in patients. 7 00:00:30,000 --> 00:00:35,458 FDA reports a lack of human exposure information for KPV drug products. 8 00:00:35,458 --> 00:00:41,333 Delivery, safety and meaningful clinical outcomes remain questions to answer before making gut-healing 9 00:00:41,333 --> 00:00:44,833 claims.